The widow of a murdered yakuza boss serves jail time for attacking the man she believes killed her husband. After her release, as she is shadowed by a hitman, she returns to thoughts of revenge.

Set in the year 2000, when the level of Labor accidents begin to escalate around Tokyo Bay, police detectives Kusumi and Hata are assigned to investigate. What they discover leads to a series of government cover-ups, conspiracy concerning a new biological weapon entitled WXIII-Wasted Thirteen and a tragic, personal connection to Hata. The only hope to stop this threat is to cooperate with the military and lead WXIII into a showdown with the Labors of Special Vehicle Division 2.