After nearly two decades of legendary criminal feats, making him France's most notorious criminal while simultaneously feeding his desire for media attention and public adoration, Mesrine becomes increasingly paranoid and isolated, leading to a dramatic confrontation with the law that ultimately seals his fate as the nation's most infamous public enemy.

Jacques Mesrine, a loyal son and dedicated soldier, is back home and living with his parents after serving in the Algerian War. Soon he is seduced by the neon glamour of sixties Paris and the easy money it presents. Mentored by Guido, Mesrine turns his back on middle class law-abiding and soon moves swiftly up the criminal ladder.