A young woman named Margaret is brutally murdered, victim of her husband's cold-blooded plot to inherit her wealth. An ages-old curse lying dormant for generations will manifest itself before his very eyes and those of Margaret's killers.

The year is 1800. The town, Bacchusville, New Jersey. Reclusive local witch Helena Pottsworth (Paige Richards) can no longer contain her surging lesbian desires, and this puritanical, post-colonial town is about to fight a revolution of the sensual kind. Using a bit of black magic and a lot of hypnotic beauty, Helena begins seducing the female citizenry in bodice-ripping acts of pagan eroticism and hot-tongued debauchery that make bodies quiver in ecstasy.

Waldo Williams returns from his Tijuana vacation to find out that he had become infected by the Notorious Mexican Butt Humping Bullfrog. After being diagnosed by his proctologist with just days to live, Waldo seeks the help of the mysterious Japanese specialist, Dr. Wansamsaki, who treats Waldo with his unorthodox methods, which involve a long nuclear rod. The next day, Waldo’s rear end starts glowing a bright green – and that’s only the beginning. Within days, Waldo’s rear end develops a mind of its own, becoming capable of breaking away in the middle of the night, committing a mur­der or two and then returning before morning, leaving a fecal trail that leads right to Waldo’s bedroom.

When a new strain of marijuana is delivered to a remote strip club, an army of insect creatures hungry for human blood starts feeding on the staff and patrons. Soon the bugs cause provocative havoc as their bite elicits a particularly potent narcotic reaction in those bitten.

Five strangers are invited to a castle under the pretense that one may inherit it. Little do they know what dangers await at the House of the Wolfman.

After his witch guardian threatens to turn him into a statue, young Tip runs off to Emerald City with his newly-animated companion, Jack. Along the way, he meets up with Genral Jinjur, leader of the Army of Revolt, who takes Tip prisoner as she marches her troops to take over the Emerald City.