The Undead Task Force (a branch of the LAPD, formed when the San Fernando Valley was overtaken by zombies, werewolves and vampires) must continue to get rid of the monsters and contain them in the valley. While this occurs, scientists work to find out what caused the outbreak. A brave camera crew comes along for the ride.

维持了四年情侣关系且已经同居一年的卡尔（基特·威廉森饰演）和汤姆（范·汉西斯饰演），因为第三者杰瑞米（马修·麦克利根饰演）而感情生变，虽然汤姆承诺将结束与杰若米的关系，但卡尔始终无法忘怀，前去与杰若米理论，甚而产生报复心而与杰瑞米发生性关系后又抱着悔意，两人各自努力的维持着这段关系但又对彼此仍有所隐瞒。另本剧另一叙事线则是关于卡尔的好闺密凯西（吴恬敏饰演）和她的男朋友伊恩（约翰·哈尔巴克饰演）的情侣关系已经维持六个月纪念日，这是凯西所拥有的情侣关系最长久的一次，但是伊恩最短的一次，两人对未来的想法不同与不安渐渐让关系发生变化。

Harriet, a comic book artist with a secret, and her reckless BFF, Reba, take their '76 AMC Pacer on the open road and instead get a wild ride towards an impending nuclear apocalypse.