Dozens of star and character-actor cameos and a message about the Variety Club (show-business charity) are woven into a framework about two hopeful young ladies who come to Hollywood, exchange identities, and cause comic confusion (with slapstick interludes) throughout the Paramount studio.

Based on the long-running radio show. Irma is a likeable airhead who meddles in her roommate's love-life. Dean Martin and Jerry Lewis, in their first screen appearance, are juice-bar operators who are discovered when a self-proclaimed manager hears Martin's golden voice. Irma's roommate wants to marry her rich boss, but instead falls in love with Martin.