故事描述了上世纪六十年代所谓的「人类性行为探索者」William Masters和Virginia Johnson的生活及对当时流行文化的影响。据称正是因为这两个人对性爱进行深入研究，才触发了当时西方社会特别是美国的「性革命」。

Ex-con Eddie Cleary gets a job working on his older brother's isolated farm. It's not long before bizarre things start happening--dead birds falling out of the sky, family pets attacking their owners, strange apparitions beginning to appear, and people who had been "normal" suddenly going insane.