The Tonight Show with Conan O'Brien is an American late-night talk show that featured Conan O'Brien as host from June 1, 2009 to January 22, 2010 as part of NBC's long-running Tonight Show franchise. The program's host, Conan O'Brien, previously hosted NBC's Late Night with Conan O'Brien, which followed The Tonight Show with Jay Leno for 16 years, until O'Brien's brief succession over Leno.Many members of the Late Night cast and crew made the transition to The Tonight Show. The Max Weinberg 7, the house band from O'Brien's Late Night, served as the house band under the new name, Max Weinberg and The Tonight Show Band. Andy Richter returned to the show as announcer, and also began resuming his role as sidekick, shortly before the show's conclusion. The opening and closing theme song from Late Night was also carried over to Tonight, in a slightly altered form.In January 2010, after the show had been on the air for seven months, it was announced that NBC was intending to move Jay Leno from primetime back to his original timeslot at 11:35 pm, with O'Brien's show starting shortly after midnight. In response to the announcement, O'Brien released a press statement saying that he would not continue as host of The Tonight Show if it was moved to any time after midnight to accommodate The Jay Leno Show. He feared it would ruin the long and rich tradition of The Tonight Show. It had been on after the late local newscasts from the beginning. After two weeks of negotiations, NBC announced that they had paid $45 million to buy out O'Brien's contract, ending both his tenure as host as well as his relationship with NBC after 22 years.

16岁少女迪迪（克里斯蒂娜·里奇 Christina Ricci 饰）的继父去世之后，迪迪立马就离开了家，她恨透了自己的母亲，也恨透了这个没有温暖的家庭。在好友兰迪（威廉姆·李·斯科特 William Lee Scott 饰）的帮助下，迪迪前去投奔自己同父异母的哥哥比尔（马丁·唐文 Martin Donovan 饰），比尔是一名同性恋者，和自己的男友迈特（伊凡·谢尔盖 Ivan Sergei 饰）住在一起。
很快，迪迪就和迈特搞到了一起，不仅如此，她还怀上了迈特的孩子。于是，迈特带着迪迪远走高飞，而迈特的前男友贾森（约翰尼·盖尔克奇 Johnny Galecki 饰）根本不相信这一切，他一位迈特失踪了，于是报了警。

作为一个电影公司的制片人，Griffin Mill（蒂姆·罗宾斯 Tim Robbins 饰）每天要从无数的剧本里面挑选极少的几部拍成电影。他最近的日子不太好过，先是Larry Levy（彼得·盖勒 Peter Gallagher饰）和他竞争日益激烈，然后又是不断收到匿名的恐吓信，让他忐忑不安。他怀疑是某个被他拒绝了的编剧所为。他把怀疑集中到一个叫David Kahane的编剧身上，于是他在电影院找到David并和他一起来到酒吧。后来两人竟争吵起来，在停车场甚至发展成打斗。在打斗中，David不慎摔下下水道身亡，Griffin只能将其伪装成是被抢劫身亡的样子。作为最后一个见到David的人，Griffin成了警方的嫌疑人，更让他恐惧的是，他还是收到匿名的恐吓信，甚至在他的车上发现了一条蛇......接下来，Griffin该怎么玩这个游戏？

迈克尔-沃克小时候希望每天都是圣诞节。直到一场悲惨的事故摧毁了他的节日精神。30 年后的今天，尽管俏皮的妻子和好心的父母鼓励他，迈克尔仍然无法在节日里获得任何快乐。但是，当他年幼的儿子面临一场悲剧时，迈克尔需要弥补他的过去。一个名叫尼克的神秘人送给迈克尔一份礼物，让他鼓起勇气找回失去的快乐。