Ellen Carson is a real estate agent who inadvertently cuts off a delivery truck driver while changing lanes on the freeway to hurry home. The truck driver turns out to be a disturbed man named Eddie Madden, who proceeds to chase after Ellen in an effort to run her off the road. Ellen in fear calls the 1-800 number on the back of his truck and lodges a complaint, which causes Eddie to lose his job, and he (being a grieving husband and father who earlier lost his family to a car accident) sets out to destroy Ellen's family and soon becomes fixated on Ellen and her teenage stepdaughter Cynthia and plots to have them as replacement family, by removing the head of the house, Ellen's husband and Cynthia's father Jim Carson.

Theresa is an imaginative, rebellious orphan from Brooklyn, who has dreams of show business success. She tries outrageous schemes to launch herself into the public eye, until finally meeting a mentor, Sammy Cohen, whose own career fizzled as a result of alcoholism.

Jackie Ivers is a Los Angeles nurse who returns home to the small town of San Vicente to find that her friends and family have taken on bizarrely different personalities. Jackie notices that everyone who goes into the town's lake come out different...

Privileged teenage friends Jenny, Nell and Stream spend their senior year on a quest to rid Stream of her virginity. However, Stream wants more than just her first sexual experience. She wants to have an orgasm -- but achieving this proves problematic, as the boys she meets are hardly sensitive enough to provide her the release she seeks. When it becomes clear that Nell and Jenny have never experienced an orgasm either, all three set out to get one.

Mitch Buchannon, believed to have died in a boating accident survived and only has amnesia, he has been recovering in a Los Angeles hospital. His new fiancée, Allison Ford, resembles his old lover, Lt. Stephanie Holden who died years ago.

Jarvis and Pepper crash land their small plane on the roof of the Bridges family. Pepper finds herself having a positive effect on the households' autistic son Andy.