Lola finds herself into the world of violence and drug trafficking when her father is murdered for refusing to put his truck to the service of a powerful cartel, with protections at high police levels. Knowing the local officials will not serve out justice, she takes matters into her own hands. Armed with a machine gun, she'll attempt to get revenge by her own hands - but the enemy has more firepower than her.

Northern Mexico, early 20th century. Reynaldo del Hierro is murdered while riding with his sons Reynaldo and Martín, whose mother instills in them the need for revenge.