Kardia weaves fiction and science to tell the story of Hope, a pathologist who embarks on a journey of reconciliation. Hope discovers that the experimental heart operation she underwent as a child has mysteriously linked her life with another. To unlock the secret of her past, Hope must revisit her childhood and explore regions of her life that have heart stopping results.

Based on the true events leading up to the murder of multimillionaire Ted Ammon found bludgeoned to death at his East Hampton estate while in the midst of a combative divorce and custody battle from his mentally unstable wife, Generosa Rand.