Shemp is a sick man, suffering from hallucinations. His worst vision is that his ugly nurse Nora is actually beautiful. When Moe and Larry come to take him home from the sanitarium, they discover he's become engaged to Nora. On the way to Nora's apartment for the wedding, the boys get in a fight with a stranger who promises to get even with them if he ever sees them again. They arrive to finding Nora waiting for her father, who, when he arrives, turns out to be the man they just fought with.

Collins College needs a new department head for their science department, so Doctors Carter and Zorch consult Thinko, the campus computer, and come up with Dr. Mathilda West, who has degrees in lots of things, but turns out to be disruptively attractive as well.

Buster and Phyllis endure a number of outdoor adventures trying to prove to each other their survival skills. The balloon, which lands Buster in the wilderness, later proves useful as their canoe is about go over a waterfall.

With little luck at keeping a job in the city a New Yorker tries work in the country and eventually finds his way leading a herd of cattle to the West Coast.