Two rich American young adults who meet and fall in love in Venice, Italy. With plenty of money and no real responsibilities or direction in life, the couple begin experimenting with illicit drugs. The movie travels through a series of flashbacks showing their progression from marijuana to harder drugs as a result of their complex romantic entanglement with each other.

Henry Orient is a madly egocentric and overly amorous avant-garde concert pianist who is hilariously pursued all around New York City by two 14-year-old fans. The girls, Val and Gil chase a harassed Henry all over the city, thwarting his afternoon liaisons with a married woman and leaving utter chaos behind them - until Val's sexually promiscuous mother appears on the scene to put a stop to the girls' shenanigans