Sully is a psychotic criminal who has just been released from prison. Now he has only one goal: revenge against police detective Elaine Reynolds, who he blames for the death of his wife's unborn child.

Ten years after the first American Pie movie, three new hapless virgins discover the Bible hidden in the school library at East Great Falls High. Unfortunately for them, the book is ruined, and with incomplete advice, the Bible leads them on a hilarious journey to lose their virginity.