An american explorer organizes an expedition to the Amazon Rainforest in search of a lost treasure.

Anjo, a millionaire playboy who moonlights as a crime fighter, leaps into action when his arch-nemesis, the Scarlet Scorpion, kidnaps a beautiful fashion designer.

Psychiatrist experiments LSD on 4 volunteers, to investigate Coffin Joe's influence over them. Each patient presents a different reaction, involving sex, perversion and sadism.