In June, 1983, in Dutchess County, New York, Sebastian Cole joins his mother, step-father, and sister for dinner. Hank, Sebastian's step-father, drops a bomb: he announces he's changing sexes. Sebastian's sister splits immediately for California, and his mother takes him back to England. Jump ahead eight months, Sebastian is back in New York, knocking on Hank's door. Hank (now Henrietta, although all the surgeries aren't complete) takes Sebastian in and is his rock over the next few months of high school. Sebastian's "adventures" are mostly self-destructive.

When a strange signal pulsates through all cell phone networks worldwide, it starts a murderous epidemic of epic proportions when users become bloodthirsty creatures, and a group of people in New England are among the survivors to deal with the ensuing chaos after.

A writer's young assistant becomes both pawn and catalyst in his boss's disintegrating household.

Just as Daniel and Kristi welcome a newborn baby into their home, a demonic presence begins terrorizing them, tearing apart their perfect world and turning it into an inescapable nightmare.