The film tells the story of two brothers, Hong Da (洪达) and Hong Yu (洪宇), who both serve in a secret anti-drug squad of the Kaniya military. During a drug sweep operation on the Southeast Asian border, they are ambushed by the cunning drug lord Gong Tai (贡泰). Hong Da, who is about to become a father, sacrifices himself to protect his younger brother Hong Yu.

Yang Gensi leads his team at the Chosin Reservoir to repel eight waves of attacks from the U.S. Marine Corps. With ammunition running low and few men left, he must make sacrifices to defend their position.

Retired special forces soldier Cheng Kai infiltrates the terrorist-held Talin stronghold searching for his missing wife, a medical worker, and with crucial aid from kidnapped girl Mirra, battles mercenaries and overcomes lethal perils to rescue her from their clutches.

电影《战刀屠狼》围绕着缉毒警察这一极其特殊的职业展开，一方面以缉毒警察蓝海与家人的亲情为线索，通过一系列错综复杂的事件，突出表现了这个孤独又危险的职业所背负的压力和责任。另一方面讲述缉毒警们面对违法犯罪，勇往直前，不惧危险的牺牲奉献精神以及深入狼穴斩断毒品交易的故事。影片揭示了邪不胜正的主旨，传递积极正能量，也让大众更加了解这个平凡而又伟大的神秘职业。

影片讲述了一名中国退伍军人的警察弟弟，在金三角地区追击毒枭团伙的过程中，英勇牺牲。哥哥誓言剿灭毒枭，在犯罪团伙的内地线人的指引下，被骗至大毒枭老巢。经过一番激烈打斗，铁血硬汉式的中国军人最终剿灭了一众毒贩，伸张了正义。