故事描述了上世纪六十年代所谓的「人类性行为探索者」William Masters和Virginia Johnson的生活及对当时流行文化的影响。据称正是因为这两个人对性爱进行深入研究，才触发了当时西方社会特别是美国的「性革命」。

The Undead Task Force (a branch of the LAPD, formed when the San Fernando Valley was overtaken by zombies, werewolves and vampires) must continue to get rid of the monsters and contain them in the valley. While this occurs, scientists work to find out what caused the outbreak. A brave camera crew comes along for the ride.

A woman's peaceful mountain getaway takes a bizarre turn when her boyfriend disappears, and a random naked man shows up claiming to be him.