影片讲述了一对双胞胎姐妹的故事。姐妹二人有着截然相反的性格和爱好。姐姐专注于学习，成绩优异，但是不善言谈。妹妹重视个性发展，目标是成为选美冠军。一次偶然的巧合让姐妹二人互换身份。两人将如何应对这个巨大的挑战？姐妹两个由最开始的互相仇视到后来惺惺相惜，是共同的遭遇和磨难让二人更加珍惜彼此，也让她们更好地学会宽容和体谅。

Two not-too-bright party girls reinvent themselves for their high school reunion. Armed with a borrowed Jaguar, new clothes and the story of their success as the inventors of Post-It notes, Romy and Michele descend on their alma mater, but their façade crumbles quickly.