Mark Twain is a documentary film on the life of Mark Twain also known as Samuel Clements produced by Ken Burns in 2001. Burns captures both the public and private persona of Mark Twain from his birth to his death. The film was narrated by Keith David and the voice of Mark Twain was provided by Kevin Conway.

Ken Burns, the premiere documentarian of Americana, tackles the life of Mark Twain, the first writer with a uniquely American voice. In this installment in Burns' "American Lives" series, the two 2-hour episodes explore a side of Twain that is unfamiliar to many. Widely regarded as the funniest person of the 19th century, Twain suffered through severe personal tragedies and lack of business sense that brought him to the brink of financial ruin on several occasions. Includes interviews with writers William Styron and Arthur Miller and actor Hal Holbrook (who has portrayed Twain in a one-man play each year for over 50 years).