主人公谢尔顿·库珀Sheldon Cooper（吉姆·帕森斯饰）和莱纳德·霍夫斯塔特Leonard Hofstadter（约翰尼·盖尔克奇饰）是一对好朋友，他们的智商绝对高人一等，因为他们对量子物理学理论可以倒背如流，无论你问他们什么问题，都难不倒他们。但是说到日常生活，这两个不修边幅的男孩就彻底没了脾气，生活中柴米油盐这些看似简单的事情，却让他们有迷失在太空里一样的感觉，他们所掌握的那些科学原理在这里根本没有用武之地。直到有一天，隔壁搬来一位美貌性感的女孩佩妮Penny（卡蕾·措科饰），顿时吸引了莱纳德Leonard的目光。佩妮Penny是个梦想成为演员的女孩，但一直没有能成功，平时只能在快餐店打工，她个性开朗，待人友善，是位与莱纳德Leonard、谢尔顿Sheldon截然不同的追求时尚的年轻人，最重要的是她刚刚变成单身。

莱纳德Leonard和谢尔顿Sheldon还有两个好朋友。自认为是花花公子的霍华德·沃洛维茨Howard Wolowitz（西蒙·赫尔伯格饰），他称自己是加州理工学院的"卡萨诺瓦"（1725-1798，意大利冒险家，以所写的包括他的许多风流韵事的《自传》而著称，后来该词被引申为"风流浪子，好色之徒"），能用六种语言泡妞，参与负责美国的火星探索计划，其实霍华德Howard不过是个喜欢拿一些过时的手段泡妞的家伙，很多时候他的泡妞手法都让对方感到恶心。来自印度的拉杰什·库斯拉帕里Rajesh Koothrappali（昆瑙·内亚饰）患有严重的“与异性交往障碍症”，有异性在场的时候他就无法说话，只有在喝醉以后才能自在地与女孩交流。一个美女和四个科学阿宅的故事就这样在笑声中悄然开始上演。

Nobody likes Ben (Jesse Eisenberg). Ben doesn’t even like Ben. He's been kicked out of grad school, lives off his parents’ money, and bullies everyone in his life, including his roommate Kalyan (Kunal Nayyar), an earnest Nepalese immigrant. When Ben discovers that his grade school crush is marrying a straight-laced banker, he sets out to destroy their relationship and win her back. The New Group, in association with Lisa Matlin, presents The Spoils, a deeply personal and probing comedy written by Jesse Eisenberg, in a world premiere production directed by Scott Elliott and featuring Jesse Eisenberg (The Social Network), Kunal Nayyar (The Big Bang Theory), Erin Darke (Still Alice), Annapurna Sriram (The Happiest Song Plays Last), and Michael Zegen (Boardwalk Empire), as the third show in the company’s 2014-2015 Season.

Nobody likes Ben (Jesse Eisenberg). Ben doesn’t even like Ben. He's been kicked out of grad school, lives off his parents’ money, and bullies everyone in his life, including his roommate Kalyan (Kunal Nayyar), an earnest Nepalese immigrant. When Ben discovers that his grade school crush is marrying a straight-laced banker, he sets out to destroy their relationship and win her back. The New Group, in association with Lisa Matlin, presents The Spoils, a deeply personal and probing comedy written by Jesse Eisenberg, in a world premiere production directed by Scott Elliott and featuring Jesse Eisenberg (The Social Network), Kunal Nayyar (The Big Bang Theory), Erin Darke (Still Alice), Annapurna Sriram (The Happiest Song Plays Last), and Michael Zegen (Boardwalk Empire), as the third show in the company’s 2014-2015 Season.

Nobody likes Ben (Jesse Eisenberg). Ben doesn’t even like Ben. He's been kicked out of grad school, lives off his parents’ money, and bullies everyone in his life, including his roommate Kalyan (Kunal Nayyar), an earnest Nepalese immigrant. When Ben discovers that his grade school crush is marrying a straight-laced banker, he sets out to destroy their relationship and win her back. The New Group, in association with Lisa Matlin, presents The Spoils, a deeply personal and probing comedy written by Jesse Eisenberg, in a world premiere production directed by Scott Elliott and featuring Jesse Eisenberg (The Social Network), Kunal Nayyar (The Big Bang Theory), Erin Darke (Still Alice), Annapurna Sriram (The Happiest Song Plays Last), and Michael Zegen (Boardwalk Empire), as the third show in the company’s 2014-2015 Season.

在经历前两部的考验之后，波比（安娜·肯德里克 Anna Kendrick 配音）和布兰（贾斯汀·汀布莱克 Justin Timberlake 配音）现在正式成为一对情侣，正当他们的关系变得越来越亲密，波比却发现布兰竟然有一个神秘的过去。他曾经是她最疯迷的男团“兄弟地带”成员，那是他和他的四个兄弟弗洛伊德（特洛耶·希文 Troye Sivan 配音）、约翰·多瑞（埃里克·安德烈 Eric André 配音）、史布斯（戴维德·迪格斯 Daveed Diggs 配音）以及克雷（卡迪小子 Kid Cudi 配音）共同组成的男孩团体。但是兄弟乐团在布兰还是的小朋友的时候就已经解散，这一家人也跟着四分五裂，从那时候起，布兰就再也没有见过他的兄弟。 但是当布兰的兄弟弗洛伊德因为他的音乐才华被两个流行音乐的邪恶大坏蛋——凡菲（艾米·舒默 Amy Schumer 配音）和凡尼（安德鲁·兰内斯 Andrew Rannells 配音）绑架之后，布兰和波比就展开一场惊险刺激的冒险旅程，希望布兰和他其他的兄弟能够重新聚首，救出弗洛伊德，不让他遭受比在流行音乐界成为过气明星更悲惨的命运。