故事发生在真人秀“老大哥”片场。浑然不知情的几位选手和工作人员，突然遭逢一大群僵尸的袭击。怪诞离奇的事情接踵而至。他们被困在密闭的狭小空间里互相尔虞我诈，却不知道屋外早已是尸横遍地的死亡之境。直到选手凯莉（杰美·温斯顿 Jaime Winstone 饰）冲进屋内，警告他们已经被僵尸包围，并随时受到生命的威胁。就在这生死攸关的危机时刻，这一群貌合神离的难兄难弟，不仅要放下各自的成见携手一致对外，更要使出浑身解数在僵尸的眼皮底下逃出生天。

Reluctant Jennifer must bathe her mischievous grandmother. Once close, they are now virtually strangers. The enforced intimacy of the situation results in an awkwardness that they can neither deny nor overcome until they begin to play together in the water.