美国国家公园一处被称为13号怪异之地的尸体农场，医学教授拉里·杰弗逊（尼克·摩根 Nick Moran 饰）带领梅根（凯瑟琳·伊莎贝尔 Katharine Isabelle 饰）、丹尼尔（布兰登·费尔 Brendan Fehr 饰）等六名学生来到这里，他们将在汤姆金斯（迈克·山克斯 Michael Shanks 饰）的指导下进行一次完全与世隔绝的罕见医学实习，一旦成功通过测试将有望在FBI谋得实习职位。当地处满了大量废弃车辆以及死状恐怖的腐烂尸体，队员们分成不同小组，按照汤姆金斯的指示取样化验。 然而令他们想不到的是，政府曾在此地进行过极不人道的生物实验，但学生们专心工作时，那些高度腐烂的死者开始苏醒，准备上演一场血腥淋漓的饕餮盛宴……

An innocent camping trip takes a dark turn for a young brother and sister, when they witness a murder. The young siblings become the killers' next target as they are chased and hunted through the wilderness. Serving time over a protest gone terribly wrong, their father, Jack Damson (Brendan Fraser), devises a plan to break out of prison and rescue his kids from the pair of criminals Tommy (Dominic Purcell, TV's "Prison Break") and Kenny (Ethan Suplee, TV's "My Name is Earl"). A fight for survival ensues in the action-packed thriller where the hunters become the hunted.

The Lunar Base Ark explores ore and unexpectedly is hit by a meteor shower and has severe damages. Colonel Gerard Brauchman sends the crewwoman Ava Cameron to repair a wing that is full of CO2. Dr. Lance Krauss warns that the gas may cause paranoia and hallucinations. Ava brings a sample of the meteor for analysis and Dr. Krauss finds that there are spores attached to the meteor. Ava accidentally cuts her finger in a sample but she hides the cut from the doctor. Soon Ava gets pregnant and delivers an alien offspring. However, neither Col. Brauchman nor Dr. Kraus believes in her words and they believe that Ava is delusional. He offspring bites the crewman Bruce Johns and the crew discovers that Bruce has been cloned by the alien. Soon they find how dangerous the clone is.

一对儿情侣本打算要度过一个浪漫假期，却不料被一股邪恶力量带入深渊.....