During the last years of World War II, Hermie, Oscy, and Benjie are coming of age. They went their separate ways when they graduated from high school in 1944. Benjie joins the Marines as Hermie and Oscy enter college. There, Hermie falls head over heels for another freshman named Julie, and the two old friends deal with a troublesome fraternity president who is in charge of hazings.

At a party, someone goes insane and murders three women. Falsely accused of the brutal killings, Jerry is on the run. More bizarre homicides continue with alarming frequency all over town. Trying to clear his name, Jerry discovers the shocking truth...people are losing their hair and turning into violent psychopaths and the connection may be some LSD all the murderers took a decade before.