When Shirley, Madea's niece, receives distressing news about her health, the only thing she wants is her family gathered around her. However, Shirley's three adult children are too preoccupied with their own troubled lives to pay attention to their mother. It is up to Madea, with the help of rowdy Aunt Bam, to bring the clan together and help Shirley deal with her crisis.

Judith has known her husband Brice since they were children, but now their marriage is growing stale. Having just completed her graduate work in psychotherapy, she's eager to begin a career as a marriage counselor. She takes an internship at a matchmaking firm for millionaires and meets Harley, a charismatic billionaire investor who makes no effort to hide his attraction to Judith. Although quite resistant at first, eventually Judith succumbs to his charms, placing her marriage in jeopardy and forever altering the course of her life.

For years, mild-mannered Wall Street banker George Needleman has meandered through life oblivious to his family's dysfunction and his company's malfeasance, but he's forced to wake up when he learns that he's been framed in a mob-backed Ponzi scheme. Placed under federal protection, George and his family are shipped down South to Madea's house, where the no-nonsense matriarch whips them all into shape using her special brand of tough love.

Eight married college friends plus one other non-friend (all of whom have achieved middle to upper class economic status) go to Colorado for their annual week-long reunion, but the mood shifts when one couple's infidelity comes to light. As secrets are revealed, each couple begins to question their own relationship.

When a law-abiding woman gets indicted for murdering her husband, her lawyer soon realizes that a larger conspiracy may be at work.

Madea winds up in the middle of mayhem when she spends a hilarious, haunted Halloween fending off killers, paranormal poltergeists, ghosts, ghouls, and zombies while keeping a watchful eye on a group of misbehaving teens.

About existence from the perspective of 20 nameless black females. Each of the women portray one of the characters represented in the collection of twenty poems, revealing different issues that impact women in general and women of color in particular.