Pi Seon Ju works as an interior designer in a small neighborhood. She is married to Jeon Nam Jin, who is an ambitious architect. Although Pi Seon Ju is devoted to her husband, her husband falls in love with Jin Sang A, who will become the successor of an architecture company. To further pursue his love and ambitions, Jeon Nam Jin demands a divorce from Pi Seon Ju. After their divorce, Pi Seon Ju decides to start her new life.

Meanwhile, architect Kim So U is married to Jin Sang A. Unlike Jin Sang A, he is satisfied with a stable situation rather than being fueled with ambition. Due to his wife's affair with Jeon Nam Jin, Kim So U gets divorced. After meeting Pi Seon Ju, Kim So U experiences a turning point in his life.

Syndrome is a 2012 South Korean medical drama series, starring Han Hye-jin, Song Chang-eui and Park Gun-hyung. It is set in the world of neurosurgery where a medical student finds herself in a love triangle with two fellow doctors. The television series aired on jTBC from February 13 to April 17, 2012 on Mondays and Tuesdays at 21:55 for 20 episodes.

One day, Yi-rang fakes a fall in a race because she was afraid of losing. After the race, she decides to never run again. Soon, Yi-rang becomes friends with Soo-min, a new student from Seoul, and starts to ask herself about her future.