Based on a notorious Belgian court case, My Friend, or The Hidden Life of Jules Depraeter follows Jules Depraeter, a charming but manipulative businessman from Ghent who becomes entangled in robbery, fraud and conspiracy. When police discover stolen jewels and securities in the trunk of a garage owner linked to him, a complex investigation unfolds. During the trial, Depraeter attempts to save himself by accusing a respected investigating judge of masterminding the crimes and plotting the murder of his own wife. Told through courtroom scenes and flashbacks, the film gradually reveals a web of lies, corruption and psychological manipulation.

A young boy coming into puberty is resentful of his mother's budding romance with the best friend of her late husband, and is torn and confused about his emerging feelings for Toni, a young girl in his neighborhood. His fascination with an antique Oriental knife leads him to steal it and he uses it to try to impress Toni while at the same time trying to break up his mother's relationhip.

The fainthearted cigar trader Ducker keeps himself quiet during World War II. That changes when parachutist Dorbeck lands in his backyard. It turns out the parachutist bears a remarkable resemblance to Ducker. Ducker follows Dorbeck blindly, becomes involved in the Dutch resistance and soon starts killing people. When he escapes through German lines to the freed South Netherlands, no one has ever heard of Dorbeck.

An independent-thinking doctor in a rural community with his own ideas of how medicine should be practiced begins to find himself ostracized from the community after one of his patients commits suicide.