Five college friends venture out on a road trip. A detour to Lisa's Uncle Marty's house leads them into the Galloway Forest which is known for mysterious disappearances and rumors of cannibalism. As Lisa experiences bizarre visions, she wonders about her darkest family secrets. The mysterious Uncle Marty has a taste for beauty and blood and nothing is as it seems as the friends become engulfed in his twisted world.

The young and lust filled Blood Sisters find college life the perfect haven for their daily "habit"... Blood. They stalk and seduce their victims by day, then torture and kill them by night. When a chain of strange dissappearances occurs at sexy Tracy's college, fear immediately floods the hallways. Corpses mount at one of the school's sororities. Tracy and her gorgeous roomate, Melissa, join the mysterious sorority hoping to uncover the dark secret. After witnessing brutal slayings, they realize their only salvation lies in the defeat and damnation of the Blood Sisters!