Moments after parachuting from Flight 777, a former Marine and a flight attendant find themselves descending into a world of madness. Panic and chaos plague the streets, cities are on fire, and they're being hunted by a team of mercenaries.

Prolific expert of the occult and whiskey, Reverend Conte, accompanies a ragtag group of military rejects to a remote South Pacific Island to investigate the disappearance of Marines units stationed there in 1944, said to be at the hands of the Japanese Imperial Army. Upon speaking with the island’s inhabitants, they soon discover the Marines had actually been massacred by a group of Lycanthropes, known to most as WEREWOLVES.