The story opens as Stony returns to his home town, only to discover that his sheriff father has been murdered by person or persons unknown. The new sheriff (Henry Brandon) resents the arrival of the Mesquiteers, going so far as to frame Tucson on a murder charge.

On Christmas Eve, a little boy named Timmy was read a Christmas story and tucked into bed. The resident mouse Gumdrop , while admiring the house all decorated for Christmas, noticed Timmy's letter to Santa on the floor. The letter must of have fallen off the table and never got mailed. So he and the family dog Gobber set outside to deliver the letter to Santa and save Christmas for Timmy.

A variety show, with the main feature being the serialized adventures of the two title characters, the anthropomorphic moose Bullwinkle and flying squirrel Rocky. The main adversaries in most of their adventures are the Russian-like spies Boris Badenov and Natasha Fatale. Supporting segments include Dudley Do-Right, Peabody's Improbable History, and Fractured Fairy Tales, among others.

Andy Panda is the painter and his dog, Butch, is the pointer, and Andy is trying to paint a portrait of Butch doing what a bird-dog is supposed to do...standing still and pointing to the game-bird. But Butch won't stand still. Andy's solution is to rig a gun to go off if Butch moves a muscle. Butch gamely resists all temptations to move but a couple of spiders carry him off in their web, with the gun going off repeatedly and peppering Butch's posterior.