Gary is a trailer park romance novelist who can't seem to sleep at night. He also thinks that he saw a monster assaulting his girlfriend while she was sleeping. People is his trailer park begin to die in their sleep. Soon, Gary's friends begin to think that he has gone crazy with all his ranting and raving and that all he needs is a good night's sleep. Gary is afraid to sleep...

While on a stakeout, hardboiled cop Eddie Boone gets injected with a dangerous new designer drug causing nightmarish side effects. As he searches for his missing partner, Eddie discovers the urban streets full of mutants, monsters, and mayhem orchestrated by the mastermind behind the lethal narcotic.