After losing her parents in a tragic accident, Zhuo Yifeng suppresses her past through selective amnesia and takes on a new identity as Su Nianfeng. Raised by her parents' friend alongside his son, Su Muyun, she struggles with an uneasy sibling-like relationship. As she navigates high school, Su Nianfeng finds inspiration in her close friend Yue Diyin, whose warmth and resilience motivate her to pursue a career in medicine despite his battle with a mysterious illness.

The major case squad within the public security organization tackles a series of perplexing cases, led by forensic expert Liao Yan and criminal psychology specialist Liang Maiqi. Both are young professionals returning from abroad, leveraging their expertise to solve unusual cases. Through close collaboration with their teammates, they navigate dangerous situations, using their intelligence and bravery to resolve crises and complete missions. Meanwhile, other young officers in the squad also develop friendships and grow personally through their involvement in solving these intriguing mysteries.

卓依风（许雅婷 饰）七岁那年，一场可怕的车祸夺走了她双亲的性命，令她沦为孤儿，这巨大的打击令卓依风的大脑产生了防卫机制，暂时抹去了这部分记忆。之后，卓依风被托付给了苏家，化名苏念风，和苏家的少爷苏牧云（任世豪 饰）一起生活。 一晃眼多年过去，苏念风和苏牧云都已经长大成人升上了高中，苏牧云是学校里的风云人物，饱受瞩目，而苏念风则默默无闻。受到好友的影响，苏念风在高三那一年突然决定报考医学院，可是，这对于她来说几乎是一件不可能的事情。虽然苏牧云嘴上对她嘲讽不断，但他却用自己的行动一直默默的支持着苏念风，在众人的努力之下，苏念风最终完成了自己的心愿。