Midhunam movie is all about Sethumadhavan (Mohanlal) who has plans to start a biscuit factory near his house. But the bureaucracy and the corruption of the officials are the hurdles in front of him. Along with that he has to solve the problems in his family, which his brother (Innocent) and brother-in-law (Jagathy Sreekumar) creates. he marries his long-term fiancée Sulochana (Urvashi) who always cribs that he doesn't have love towards her, which he had shown before their marriage. How sethumadhavan succeeds in his life beating all the odds against him forms the rest of the story.

Hari's and Ganga's mobile phones got exchanged accidently and they started getting misleading calls....

Padmanabhan reunites with his son after many years of separation, but his happiness is short-lived when he realises that his son is mentally ill.

Enroute Madras via train, when three friends get falsely accused of a mysterious homicide, they escape and desperately search for the real killer.

Shyam, a flirt, seeks his friend's help to date several girls at the same time. However, an unexpected turn of events changes their situation and, later, they get caught in their own web of lies.

Sagar, known as Jackie, among the criminal underworld, is called by his friend Indu to rescue her husband Manu from the Rozario gang, who kidnapped him. Jackie rescues Manu with ease, but it ensues a gang war.

Alex, who is awaiting execution, confesses to having committed six out of the seven murders he is acquitted for. Officer Sethurama Iyer decides to trace the original murderer of the seventh one.

Aravindan, Chandu and Joy are best friends. Their friendship faces a testing time when Aravindan's sister falls in love with Chandu.

A story of homecoming from late 1970s, when 10 year old Vicky arrives at his grandparents home in rural Kerala to attend his grandfather's funeral. The disjointed family gathers together for the sixteen day long funeral period. During this period, Vicky discovers more about himself, his family and culture than he had expected to. The journey is narrated through the memories of an adult Vicky who returns to the same house to recount the experience.

Solomon, a timid villager, who lives a simple life, befriends a man who is completely opposite to him. He observes the latter's tough nature and soon his outlook towards life changes.

Vasco and his family witness a murder carried out by a local goon. Problems start brewing in their lives when this criminal starts plotting against him.

A man leading a happy life with his loving wife and two children suddenly starts getting forgetful and lost. Then, he is diagnosed with Alzheimer's disease leaving his family devastated.

Years after graduating from college, a few friends from across the world decide to get together for a reunion. But on the night of the reunion, one of them attempts suicide and goes into a coma.

Poovalli Induchoodan (Mohanlal) is sentenced for six years prison life for murdering his classmate. Induchoodan, the only son of Justice Maranchery Karunakara Menon (Thilakan) was framed in the case by Manapally Madhavan Nambiar (Narayanan Nair) and his crony DYSP Sankaranarayanan (Bheeman Raghu) to take revenge on idealist judge Menon who had earlier given jail sentence to Manapally in a corruption case. The story begins with Induchoodan released and his father & mother coming to stay with him.

Ten interconnected short stories unfolding around a roadside railway café in Kerala, where travelers from diverse backgrounds pass through, their lives briefly intersecting amid themes of migration, relationships and modern struggles.