Nora Barkin is an aspiring actress who supports herself by working for a courier service. No sooner has Nora's friend and coworker Bill Reagan jubilantly announced that he possesses a lottery ticket worth 13 million dollars than Bill is killed by an unknown assailant. Though discouraged from doing so by investigating detective Marinello, Nora insists upon trying to solve Bill's murder herself.

Harry Woltz is a homicide cop with a gambling problem; a problem that leaves him owing a great deal of money to the Russell brothers. To clear the debt they ask him to train John Farrow to murder his wife, Evans, without leaving the usual clues or making the usual mistakes. However when Harry's ex-partner is put on the case, she begins to get closer than Harry had thought before the case takes some unexpected twists.

Dead by Monday is a darkly comic tale of love and death... but not necessarily in that order. Julie is a sweet, vulnerable young woman who lacks confidence and is obsessed with the memory of her dead husband whom she idealizes. Alex is an angry writer. Talented but unable to repeat the success of his first novel, he has nothing left to say. Or live for. He just wants to die. Fate introduces these two lost souls at the edge of a cliff. While picking flowers Julie accidentally falls off. Alex, who has come to blow his brains out, is interrupted by her cry for help, just before he pulls the trigger.

A virus causes people to age rapidly. There is an antidote, but it has to be taken daily and is under control of a single company. A woman who is not infected carries an infected child, and seeks for it to be cured. This quest leads her to the blue lands, where most of the infected live.

莎朗（詹妮弗·洛佩兹 Jennifer Lopez 饰）是一位精明强干的女警，被安排到了犯罪率最高的芝加哥南部地区，在那里行使她惩奸除恶弘扬正义的责任和权利。虽然莎朗在事业上干得十分出色，深受上司和同事们的信任和赏识，但她和家人之间的关系却十分淡漠。更糟糕的是，曾经的一 段痛苦的回忆一直笼罩着莎朗，令她时时陷入绝望之中。 凯奇（吉姆·卡维泽 Jim Caviezel 饰）是一个游荡在城市街头的失意人，他关照陌生人和邻居，在一次警匪追逐中意外救下莎朗，两人由此相识。然而，过去的一场灾难让他失去了妻子和女儿，同时逝去的还有他的记忆，这使得凯奇十分痛苦。在莎朗的帮助之下，凯奇终于鼓起勇气决定寻找惨剧的真相，与此同时，莎朗那灰暗的过去亦渐渐浮出水面。