International master thief, Simon Templar, also known as The Saint, is asked by a desperate rich man to find his kidnapped daughter. However, in addition to evading the authorities, Simon must face a dangerous adversary from his past.

The residents of a rural mining town discover that an unfortunate chemical spill has caused hundreds of little spiders to mutate overnight to the size of SUVs. It's then up to mining engineer Chris McCormack and Sheriff Sam Parker to mobilize an eclectic group of townspeople, including the Sheriff's young son, Mike, her daughter, Ashley, and paranoid radio announcer Harlan, into battle against the bloodthirsty eight-legged beasts.