Successful writer and scholar Jonathan Merrick falls under the spell of the irresistible, bewitchingly beautiful Ligeia. She's fighting a fatal illness and she will stop at nothing to defeat death, her one true enemy. She steals other people's souls and on her quest to immortality she tricks Jonathan into supporting her work, breaking him apart from his fiancé Rowena and pulling him into her dark, mysterious world. They settle down in an old manor by the Black Sea where Ligeia's everlasting presence slowly drives Jonathan to madness

Joel, his cynical best friend, Nick, and easy-going little brother, Jamie, are contemporary cavemen who live in the suburban south and simply want to be treated like ordinary thirty-something guys. Despite their attempts at assimilation, Nick doesn't believe mainstream society will ever completely accept them, Jamie seems to take it all in stride and Joel straddles the middle, torn between his friends, his more traditional values and his loving fiancée.