Little Iodine does her best to break up the marriage of her parents, ruin a romance and cost her father his job.

Holding a grudge against Robert Torrens and his wife, who live in Italy, a member of the Mafia kidnaps their infant daughter Lois. Fifteen years later, after having been raised by Italian peasants, Lois, now called Peppina, dresses as a boy and stows away on a ship to America in order to avoid a marriage to a particularly loathsome count. While aboard ship she befriends Hugh Carroll, an assistant district attorney, who arranges first-class transportation for the "boy." In New York, she once again meets her kidnapper, who fled to America after the crime. He forces Peppina to maintain the masculine disguise and to pass counterfeit bills for him, for which she is arrested. Peppina gladly exposes the kidnapper's operation to the authorities, one of whom, Hugh, recognizes her as the "boy" he met on the ship. Then, once the kidnapper has been apprehended, Peppina is reunited with her parents, after which she and Hugh, who has finally discovered that she is female, get married.

In the 1860s, Mary Marlowe defies her father's wishes to marry a British lord and runs away with clerk John Carlton as he heads West to make his fortune. Mary and John endure the difficult journey and settle into a small cabin, then face the hostilities of a cattle rustling gang, as well as the tragic loss of their only son. With Mary's help, John defeats the gang, which propels him to political power that, over the years, gradually erodes the once-happy marriage.

Little Sara Crewe is placed in a boarding school by her father when he goes off to war, but he does not understand that the headmistress is a cruel, spiteful woman who makes life miserable for Sara.

A spoiled young rich girl is forced by misfortune to fight for survival in the slums and alleys, where she becomes involved with all manner of unpleasantness.

An American boy turns out to be the long-lost heir of a British fortune. He is sent to live with the cold and unsentimental lord who oversees the trust.

A young American has her ship torpedoed by a German U-boat but makes it back to her ancestral home in France, where she witnesses German brutality firsthand.

Angela maintains a coastal lighthouse in Italy, where she awaits the return of her brothers from the war. She learns they are casualties and takes solace in the arms of an American sailor washed ashore. However, the sailor turns out to be a German spy, and she is torn between her love for him and her realization that he is part of the enemy force that has destroyed her family.

The tenements are home to an international community, including the friends and family of a tough young ragamuffin named Annie Rooney, but their neighborhood may be threatened by a dangerous street gang.

A woman wakes up in the middle of the night on board a train, but she can't remember how she got there. Danger and suspense ensue.