A lovelorn paramedic rescues a woman left for dead after a deadly assault. When she refuses to go to the hospital, he takes her in, nurses her back to health and soon falls in love with her. Before long the mysterious woman suffers withdrawal symptoms, leaving the paramedic to believe his newfound love is a drug addict. Coming home to find a blood-drained corpse on his floor, he learns she does indeed have an addiction problem but it's not to drugs...

In 1986, a young breakdancer falls into a coma after hitting his head in a talent show. 20 years later, he awakens and attempts to revive his dance team's short-lived career in order to support his parents' failing yogurt shop.

It is freshman year at Coolidge College and Van Wilder is ready to party. To his dismay, all the girls have taken a vow of chastity and the dean rules the school. Van embarks on a crusade to land the campus hottie, Kaitlin, and liberate his school from sexual oppression and party dysfunction.