A married couple are traveling on a deserted desert road at night. They stop at a diner and the husband goes to the men's room. He never returns and the wife begins to suspect serious foul play.

As the three chosen defenders of Earth travel to Shang Tsung's island, Rayden teaches them how to become the masters of their destinies, overcome their foes, and control their powers. Liu Kang, Sonya Blade and Johnny Cage must defeat Shang Tsung, Sub Zero, Scorpion and Goro in a tournament of Mortal Kombat if they are to survive and save the fate of the earth.