Desperate for an heir, England's King Henry VIII shuns his wife Queen Katherine and casts his eye on the alluring Anne Boleyn, while Cardinal Wolsey's loyalty to the Catholic Church and the Pope strains his relationship to the king.

Henry and the court go to the summit to sign the treaty with France. Tensions are understandably high, and tempers of both kings flare up more than once. Meanwhile, Henry takes on a new mistress named Mary Boleyn. He soon tires of her and her father summons her sister Anne to court and tells her to find a way to keep the king's interest.

Henry's marriage to Jane Seymour is happy, fruitful and tragically short; the king brutally suppresses a rebellion against his religious reforms; England, Spain and the Pope ally against England, forcing Henry to marry a Protestant.

Henry's marriage to randy, unfaithful teenager Catherine Howard ends in her swift execution, but he finds domestic tranquility at last with the steady Catherine Parr; a war with France and Brandon's death signal Henry's waning days.