2002年，风骚律师索尔在遇见毒师“老白”之前的故事。那时他的名字叫詹姆斯·摩根·麦吉尔，人称吉米，他只是一个无名小律师。本剧将描述本性善良的律师“吉米”转变为游走在法律边缘的无良律师“索尔”的过程。

Walt must deal with the chain reaction of his choice, as he and Jesse face new and severe consequences. When danger and suspicion around Walt escalate, he is pushed to new levels of desperation. Just how much higher will the stakes rise? How far is Walt willing to go to ensure his family's security? Will his grand plan spiral out of control?

High school chemistry teacher Walter White's life is suddenly transformed by a dire medical diagnosis. Street-savvy former student Jesse Pinkman "teaches" Walter a new trade.