The Return of Jezebel James is an American situation comedy television series, starring Parker Posey as a successful children's book editor who, unable to have children herself, asks her estranged younger sister to carry her baby. The series was created by Amy Sherman-Palladino of Gilmore Girls fame, who also directed the pilot, and executive produced the show with her husband, Daniel Palladino. The show was produced by Regency Television and Dorothy Parker Drank Here Productions.

The show premiered on the Fox television network on March 14, 2008 as a mid-season replacement. After airing only three episodes, it was cancelled due to what FOX called unacceptably low ratings.

The remaining four unaired episodes were released on Apple iTunes on May 6, 2008.

College freshman Sydney White arrives at Southern Atlantic University, determined to pledge her late mother's sorority. Unfortunately, she finds that the sisterhood has changed since her parent's day. Banished to a condemned house, Sydney joins forces with seven outcasts to take over the student government and win equal rights for nerd and noted alike.