Fitzcarraldo is a dreamer who plans to build an opera house in Iquitos, in the Peruvian Amazon, so, in order to finance his project, he embarks on an epic adventure to collect rubber, a very profitable product, in a remote and unexplored region of the rainforest.

As the railroad builders advance unstoppably through the Arizona desert on their way to the sea, Jill arrives in the small town of Flagstone with the intention of starting a new life.

Guido Anselmi, a film director, finds himself creatively barren at the peak of his career. Urged by his doctors to rest, Anselmi heads for a luxurious resort, but a sorry group gathers—his producer, staff, actors, wife, mistress, and relatives—each one begging him to get on with the show. In retreat from their dependency, he fantasizes about past women and dreams of his childhood.