Based on the true story of Matthew Winkler, a beloved minister who, in 2006, was found shot and killed in his Selmer, Tennessee home, his wife and young daughters missing. Authorities soon zeroed in on Matthew's wife, Mary, as the prime suspect in the murder. After her capture, the residents of Selmer were left to wonder what would drive Mary to shoot her husband in the back as he slept. They would get their answers during her trial, when what went on behind the closed doors of this seemingly perfect family was revealed for all to see.

Ace, a 12-year-old boy is new in middle school. His grandfather from Transylvania passes away at the ripe age of 99, and sends him his dog, Fang, to look after. Ace soon discovers that Fang is a vampire dog. Professor Warhol, a mad scientist and her bumbling assistant Frank, try to capture Fang to steal his DNA, in order to look young.

Emily（麦米·古默 Mamie Gummer 饰）刚从医学院毕业，来到来到丹佛纪念医院担任一名实习医生。她以为自己终于可以放下高中时代宅女的装束，成为一位有作为有魅力的单身女医生。但她很快发现成人的世界和校园生活其实并没有太多不同，甚至更加纠结混乱。虽然她在医学院里暗恋的男生Will（贾斯汀·哈特雷 Justin Hartley 饰）也在这里实习。但外科主任Tim Granger（杰克·科尔曼 Jack Coleman 饰）对属下要求颇高，有时甚至会出言威胁，大家都十分惧怕他。医院更是派来外科专家Micah（迈克尔·拉代 Michael Rady 饰）指导和监督实习医生。
Emily是否能够成功达成自己当初的梦想？