Ph.D. candidate in Physics Mu Cheng He catches a third-year student in English Xue Tong cheating on an exam. When he even becomes the substitute teacher in her elective course Russian and makes her study with him after classes, her hatred for him only grows. Over time, however, Xue Tong discovers Teacher Mu’s true character and comes to secretly love him.

Yu Zhou Zhou, a math prodigy, defies her teachers and family's expectations and elects to study liberal arts. Though the transition from math & science to liberal arts major is difficult, she found joy in the new challenges, as well as making new friends and reconnecting with old ones.

Geng Geng is a normal high school student trying to find her place in the world. Her father just remarried and she's adjusting to her new family. She's struggling with her assignments at her new prestigious high school and she's feeling quite lonely. On the first day of school, she meets a cute boy Yu Huai and they start off on the wrong foot but quickly he becomes one of her many new friends. She even attracts the class rebel Lu Xing He and he announces his love to the world. Daily school life becomes quite enjoyable but when school ends, will she find love with the boy she always crushed on or the one who was always there for her?

The drama tells the story of Shi Guang who discovered an ancient go board by coincidence and thus got to know Chu Ying, a go player who has been entrenched in the go board as a "soul" and who has experienced thousands of years. Under his influence, he gradually confronted the story of interest in go and inspiring to become a professional go player.

本片在叙事结构上不同于常规的青春爱情片，平行讲述了三对不同年代情侣的爱情故事，而一间失恋杂货铺将看似毫无交集的三代人联系在了一起，在时空转换和穿插叙事中，展现了文革以来各代国民的恋爱风貌。

《非处方青春》是一部以当代医学院大学生为背景的青春剧，展现中国大学生积极向上的精神面貌，表现一群青年们怎样一步步从稚气未脱的孩子成长为承担起救死扶伤的白衣战士。

一晃眼时间来到了数年后，此时的白霖（张樟 饰）已经升入了大四，正在青山学院经历她的实习期。在这个节骨眼上，李佳航（李欢 饰）再度出现在了她的身边，虽然白霖一直对李佳航的付出十分的抗拒，但后者却从来没有因为白霖的态度而改变过自己的感情。
即将毕业之际，白霖遭到了同学的算计而失去了拿奖学金的机会，虽然受到了重大的打击，但白霖却并没有自怨自艾，而是将所有的心思都放在了找工作上，踏踏实实的她最终获得了应得的回报。而命运的红线将李佳航再度带到了白霖的面前，这一次，他们能否珍惜这来之不易的机会呢？

九十年代初期，随着改革开放深入，信息产业发展掀开新的一页。燕京大学计算机研究所的两个青年萧闯（吴磊 饰）与裴庆华（侯明昊 饰）从偷做汉卡入行，被主任谭启章选中，跻身电脑销售的大潮。以二人为首的众研究员瞅准时机，搭上政策春风，从代理国外电脑做起，向自主研发过渡，从草根蜕变成一代商业奇才的故事，同 时记载了20世纪末中国快速发展的那段历史。

少女何洛机灵俏皮但功课欠佳，却不小心夸下海口要考入名校。意气飞扬的学霸章远看似自大高傲，但被何洛的锲而不舍打动，辅导她不断进步。两个人心意渐明，约定报考同一所大学，但阴差阳错，高考令他们分隔两座城市。他们不畏时空距离，满怀憧憬地一起规划未来。高中同班的一众好友，也各自经历成长中的种种磨砺与挑战。高考失利的章远急于证明自己，实现早日与何洛团聚的承诺，却在创业过程中一再受挫。不同的经历和心境让他和何洛产生分歧，相互深爱却渐行渐远。站在人生的岔路口，他们应该如何抉择？数年后事业有成却天各一方，再次重逢时，心中是否还有最初的悸动？一段绵延十年，隔山跨海的眷恋，带你重温青涩时光里的怦然心动，体会追逐梦想的奋力拼搏，回想记忆深处，最初爱过的那个人。

耿耿（何蓝逗 饰）是一名技艺十分精湛的女摄影师，在学生时代，她有过一段无疾而终的青涩恋情，这段恋情至今依然深深的影响着耿耿。时间转回数年前，彼时的耿耿还是身穿校服的懵懂少女，在老师的安排下，她和学校里成绩最好的帅气男孩余淮（陈飞宇 饰）成为了同桌，他们一个是学渣，一个是学霸，互补的性格令两人之间很快就碰撞出了火花。
随着时间的推移，耿耿和余淮的感情从最初的友情一步一步的成长，两人许下了美好的约定，约好了考入同一所城市的同一间大学。然而，在约定之日的那一天到来之时，余淮竟然人间蒸发了，从此音信全无。