Peyton and Barney are fun loving high school students working on a science project with white mice. When one of the mice begins to move food toward itself with out touching it, Barney finds he has accidently discovered a formula for telekinetic powers. Now, how much trouble can a high school boy who can move things with just his mind get into?

The history of American popular music runs parallel with the history of a Russian Jewish immigrant family, with each male descendant possessing different musical abilities.