They Are Lost to Vision Altogether acts as erotic retaliation on legislation such as the Supreme Court sodomy ruling — declaring the private bedroom as open target for the State — or the Helms Amendment — the U.S government's refusal to fund explicit AIDS prevention information for gay men, lesbians and IV drug users. An attempt to reclaim eroticism and to address the contradictions of sexuality and romance in the face of a monolithic and culturally compulsory heterosexuality, They Are Lost To Vision altogether finds queer history where it can and invents the rest.

This examination of a famous scandal from the 1970s explores the relationship between Barbara Baekeland and her only son, Antony. Barbara, a lonely social climber unhappily married to the wealthy but remote plastics heir Brooks Baekeland, dotes on Antony, who is homosexual. As Barbara tries to "cure" Antony of his sexuality -- sometimes by seducing him herself -- the groundwork is laid for a murderous tragedy.