In New York, detective Alex Scott is investigating with his partner Sergio Perez the disappearance of several children. When they visit the Mexican witch Gloria, the woman advises that a powerful evil force is chasing the reincarnation of her son and drowning the other children to bring pain to their mothers.

Archaeologist Nicholas Zavaterro and his student find an antique vase with an inscription that points to where Noah's Ark is hidden. They decide to go looking, but things get out of control when they encounter opposing forces, including a monster named Tama.

During a failed art heist, the Djinn is once again liberated. This time, to complete the 1001 wishes that he needs before the final 3, he lets himself go to prison, where he starts his evil reign twisting the hopes of the prisoners. Meanwhile, the woman who set him free accidentally, Morgana, tries to find a way to stop him, aided by a young priest.