Englishman Adam and his American bride Sarah are about to embark on the romantic honeymoon of a lifetime in Venice, Italy. But when the newlyweds’ trip is gatecrashed by Adam’s excessively needy best friend, Ed, it inadvertently turns their perfect lovers’ holiday into a complete disaster.

Two sisters find their wealthy aunt is terminally ill and plan to get their inheritance, the sisters plan to improve their relationship, but when they find that they are not the only ones in the family with a similar plan.

While trying to make his sister's wedding day go smoothly, Jack finds himself juggling an angry ex-girlfriend, an uninvited guest with a secret, a misplaced sleep sedative, and the girl that got away in alternate versions of the same day.