Entropy is a semi-autobiographical film which tells the story of a young director struggling to make a film for a despotic studio while his life falls apart around him. Along the way, he goes on tour with U2 to help them make a music video, gets married in Vegas, and has a conversation with his cat.

Hell's Kitchen, New York. Terry Noonan returns home after a ten-year absence. He soon reconnects with Jackie, a childhood friend and member of the Irish mob, and rekindles his love affair with Jackie's sister Kathleen.

Nerdy high schooler Jerry Mitchell is assigned to write an article for the school paper about the infamous new delinquent transfer student, Buddy Revell. When Jerry accidentally invades Buddy's personal space and touches him, Buddy challenges Jerry to an afterschool fight in the parking lot, which Jerry tries to avoid at all costs.