Misty and Ruby are a couple who run a lesbian bar in New Jersey when their lives change one night with the arrival of a seductive woman (Anoushka) who bites Misty, thus starting her slow transformation into a werewolf. Anoushka the werewolf returns to her home in London, England where she gives an interview to a young reporter about her life as a werewolf, while back in America, Misty undergoes a slow transformation into a werewolf herself which may lead to danger for Ruby, and any other woman involved.

When a new strain of marijuana is delivered to a remote strip club, an army of insect creatures hungry for human blood starts feeding on the staff and patrons. Soon the bugs cause provocative havoc as their bite elicits a particularly potent narcotic reaction in those bitten.

Mean and domineering Jane and the sweet and ditsy Jackie are two radically contrasting sisters who suffer from severe trauma after witnessing the murder/suicide of their parents as well as seeing their other sibling Janice raped and killed by her assailants. The pair are deemed fit to re-enter society and get released from a sanitarium where they have undergone extensive rehabilitation therapy. However, Jane and Jackie prove to be anything but sane and harmless as they embark on a vicious spree in which they torture, murder, and mutilate any man luckless enough to cross their lethal paths.

Lucinda Regis, Director of Development at MALCO Oceanic Research, becomes the target of a dangerous killer after unraveling a sinister plot to inject sharks with human DNA.